Sassuolo vs. Spezia (Saturday, 2.00pm)
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In search of a first win since early January, Sassuolo welcome Spezia to the Mapei Stadium on Saturday afternoon determined to get their challenge for a European place back on track.
Their Ligurian visitors have begun to tail off of late too, and have picked up just a single point from their last three league outings.
We say: Sassuolo 2-1 Spezia
Sassuolo's once-prolific attacking output has dimmed significantly since Domenico Berardi has been unavailable, so facing Spezia's dubious defence - now also short of several men through injury - could prove a shot in the arm for the Neroverdi.
Both sides like to keep the ball, but the greater technical ability and incision Roberto De Zerbi can call upon should decide this game in Sassuolo's favour.
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Atalanta vs. Torino (Saturday, 2.00pm)
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Atalanta BC followed two of their best results this season with a couple of damp squibs in the past week, so prepare for the visit of struggling draw specialists Torino on Saturday determined to claim maximum points.
While La Dea are theoretically still in contention on three fronts, the visitors' only remaining aim for the rest of the campaign is to steer clear of the trapdoor to Serie B.
We say: Atalanta BC 2-1 Torino
An appealing battle of the wing-backs - with any one of Atalanta's rotating cast of talented wide men coming toe-to-toe with Torino's Wilfried Singo and Cristian Ansaldi - could be a highlight in this clash of two sides battling at opposite ends of the table.
The hosts' greater attacking options should decide things in their favour, but not before a hard-fought tussle with a Toro team desperate to end their winless streak.
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Juventus vs. Roma (Saturday, 5.00pm)
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Juventus pursue a sixth straight victory on Saturday evening, as they host fellow Scudetto challengers Roma amid a daunting run of fixtures.
Their visitors have bounced back from suffering derby defeat and an embarrassing cup exit to post two consecutive Serie A successes in the past fortnight.
We say: Juventus 2-1 Roma
Amid their toughest run of the season so far, Juventus seem to be approaching something closer to top form and can capitalise on Roma's all-too apparent deficiencies when facing the best sides.
In particular, the threat posed by wide men Juan Cuadrado and Federico Chiesa should occupy Roma's raiding wing-backs enough to keep the momentum trending in Juve's favour for most of what is set to be an absorbing 90 minutes of action.
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Genoa vs. Napoli (Saturday, 7.45pm)
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Serie A's most improved team will welcome Scudetto outsiders Napoli to Stadio Luigi Ferraris on Saturday, as Genoa look to continue their recent renaissance under new coach Davide Ballardini.
Having won three of their last four in the league without conceding a goal, the hosts have risen to 14th in the standings thanks to their new-found solidity, while the visitors hope to improve after an inconsistent January.
We say: Genoa 1-1 Napoli
Given Genoa's new-found resilience and lighter workload relative to their visitors, the transformation under Davide Ballardini can continue with a draw against high-flyers Napoli this Saturday.
With at least half an eye on next week's high-profile meetings with Atalanta and Juventus serving to distract Gennaro Gattuso's side, they may have to settle for a point on the notoriously lumpy Marassi pitch.
