Reading manager Nigel Adkins has made two changes to the side that lost to Sheffield Wednesday last week, with Adam Federici and Michael Hector replacing Jake Cooper and Mikkel Andersen.
Hal Robson-Kanu misses out through injury, while Danny Guthrie recovers to make the bench.
Wolverhampton Wanderers, meanwhile, welcome George Saville and Leon Clarke into their starting lineup.
The duo come in for Dave Edwards and Nouha Dicko, who suffered a pulled hamstring in Wolves' win over Bolton last week.
The visitors are unbeaten in their last six games, winning four.
Reading: Federici; Gunter, Obita, Hector, Pearce; Akpan, Norwood, Taylor, Blackman; Cox, Murray
Wolverhampton Wanderers: Ikeme; Doherty, Batth, Stearman, Golbourne; McDonald, Evans, Henry, Saville, Sako; Clarke.
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